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Of note, in the computational model, the loss of HMOX1, whose essentiality in the Fh1-deficient cells has been previously shown 8 , was expected to exacerbate the decreased ability of the FH-deficient cells to produce NADPH

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To aid in eyelid closure, its very important to continue to keep the eyes lubricated, as dry eyes are very uncomfortable and often the first symptom of incomplete eyelid closure

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