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[DOI] [PMC free article] [PubMed] [Google Scholar] 215.Chen Y., Li J., Zhang M., Yang W., Qin W., Zheng Q., Chu Y., Wu Y., Wu D., Yuan X

When you push your body too hard without giving it enough energy, it may prioritize essential functions over maintaining a regular menstrual cycle

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The consequence of these processes is the intensification of NF-b and MAPK signaling pathway activation and increased expression of proinflammatory cytokines (TNF-, IL-1, and IL-6) [123, 141, 142]

The next two would be heat and cold, which I already talked about, right