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Additionally, our findings show that RW retained its polyphenol-derived antihyperglycemic properties

The most appropriate initial response is to ask, "What is your understanding of what your hemoglobin A1c should be?" The patient's statement reveals a significant discrepancy between clinical reality and her personal perception of disease control

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Third, translational gaps between preclinical models and clinical practice are prominent: most therapeutic candidates (e.g., natural products and repurposed drugs) have only been validated in rodent models, with limited data on human renal tissue responses, optimal dosing windows, or potential drugdrug interactions in clinical settings (e.g., in patients undergoing kidney transplantation or cardiovascular surgery)

M., Sajjakulnukit, P., Li, S., Crespo, J., Nwosu, Z