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2.7 Other retinal vascular diseases Ferroptosis is also involved in the pathogenesis of other retinal vascular diseases, such as air pollution associated retinal vascular diseases (Gu et al., 2022) and oxygen-induced retinopathy (Vahatupa et al., 2023)

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doi: 10.1007/s00726-011-1046-4 74

This process produces particles with uniform sizes while requiring lower temperatures and achieving better biocompatibility

(2017a, b), rats exposed to drinking-water containing aspartame at a dose of 240 mg/kg for 2 months showed a decrease in triiodothyronine (T3) levels and an increase in thyroxine (T4) and parathyroid hormone levels (Lebda et al., 2017a), as well as upregulation of leptin, adiponectin, and peroxisome proliferator-activated receptor gamma (PPAR) mRNA gene expression in adipose tissue (Lebda et al., 2017b)

Given that zinc deficiency is more prevalent in the elderly, ensuring adequate zinc intake may be particularly important for maintaining neutrophil function and reducing susceptibility to infections in older adults