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While some authors report that there is no difference in the relapse rate but simply a longer interval without relapse for the treatment of ulcerative colitis with probiotics such as Escherichia coli Nissle 1917 or Lactobacillus GG, others accept that supplementation of medical treatment with Bifidobacterium spp

For example, mtROS and oxidized mtDNA released during Candida infection serve as potent activators of the NLRP3 inflammasome, driving IL-1 and IL-18 secretion (Westman et al., 2020)