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doi:10.2174/0929867325666180313105949 [PubMed] [BenthamScience] Zhang H, Tsao R

NAD+ for fatigue, metabolic dysfunction, and neurological support

Figure 2 shows the central mechanism of iron-driven ferroptosis in EMS tissue, where excess iron catalyzes the Fenton reaction to produce ROS, which in turn causes lipid peroxidation and membrane rupture