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In gastric cancer, ablation of a CD44 variant (CD44v) diminishes membrane xCT and suppresses tumor growth accompanied by a greater expression of phospho-p38 MAPK and upregulation of p21 in the cancer cells that adopt a more differentiated and less proliferative state (230)

Meanwhile, the efficacy of this pathway can potentially be modulated by the biochemical nature of sialic acids present (Neu5Ac vs

In line with this observation, HOP1 TPR1 HA co-immunoprecipitated with LET7 TPR FLAG (Fig

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Finally, the potential antiulcerogenic effect of astaxanthin should also be confirmed using other models of gastric ulcer