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doi:10.1002/mus.26764

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As mentioned above, the first is stimulation of the AT1 receptor by angiotensin II which further activates phospholipase C and its activation leads to an increase in cytosolic Ca 2+ concentration

In addition, tamibarotene (a synthetic retinoid) is from the same family as ATRA, but is more potent and chemically stable than ATRA

FIGURE 2 4.1 Nrf2 and oxidative stress Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important intracellular transcription factor and regulator of the antioxidant response, which is involved in ATO-induced oxidative liver injury (Yang et al., 2017a)

Eur J Dermatol 6:184190