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For this reason, smaller organoid systems may be preferred at the expense of low cellular diversity, loss of long-range connectivity, and electrophysiological properties that do not fully recapitulate disease states [225, 226]

Rasburicase-associated methemoglobinemia Rasburicase is a recombinant urate oxidase enzyme that: Lowers uric acid levels by converting it into allantoin, a water-soluble compound that can be excreted in the urine

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It was found that KEAP1 was poly-ubiquitinated, and the ubiquitinated modification level of KEAP1 increased with SP in a dose-dependent manner

The comparison of median AUCs derived from the time-course curves did not reveal any significant difference between the groups ( p = 0.132)