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Notably, other banned substances from the S4.1 group, such as aminoglutethimide, arimistane, formestane, or testolactone, may also be present in illegal samples purchased by athletes

niaaa.nih.gov Exercise-induced dehydration and blood/plasma volume changes

For a large number of people, the answer is a resounding yes

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They are caused by repeated contraction of the nasalis muscle and can become more prominent over time

Li W, Song Y, Cao YN, Zhang LL, Zhao G, Wu DT, Zou L