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Description

GPX specifically catalyses the reduction of lipid hydroperoxides (LOOHs) and organic hydroperoxides (ROOHs) through glutathione (GSH)-dependent reactions, thereby minimising oxidative damage and regulating prostaglandin biosynthesis [28]

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Vercammen D, Beyaert R, Denecker G et al (1998) Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor

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doi: 10.1016/0003-9861(52)90042-8 54 MhamdiA.HagerJ.ChaouchS.QuevalG.HanY.TaconnatY.et al

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The results demonstrated that conditioned medium from MPP+-treated microglia substantially induced neuronal apoptosis and impaired cellular viability, whereas conditioned medium from irisin-treated microglia significantly reduced neuronal apoptosis and enhanced cell survival (Fig

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