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386,387,388,389 Among these mediators, IL-6 can stimulate amyloid precursor protein (APP) formation, and is often co-localized with A plaques in AD patients

Protect against oxidative damage and helps balance free radicals

With age, autophagy naturally declines, accumulating dysfunctional mitochondria, increasing oxidative stress, and heightening inflammation, collectively called inflammaging [143]

Quercetin inhibits kidney fibrosis and the epithelial to mesenchymal transition of the renal tubular system involving suppression of the Sonic Hedgehog signaling pathway

Genomics 25 , 743745 (1995)