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Symptoms of psycho-logical distress andsuicidal ideation among banana workers witha history of poisoning by organophos-phateor n-methyl carbamate pesticides

10.1126/science.1260144 Science 11 BelloneM.BreviA.HuberS

Consequently, UPR is activated to resolve this protein-folding defect and thus to restore ER homeostasis

A number of plausible anti-cancer mechanisms have been proposed, such as indirect generation of hydrogen peroxide, enzyme cofactor activities (e.g., collagen synthesis, HIF hypoxic response regulation, TET and JHDM epigenetic regulation), as well as antioxidant and anti-inflammatory functions

Treatment-nave patients saw a median DoR of 13.4 months with a 78% ORR, while patients previously treated with platinum-based chemotherapy had an ORR of 63% and DoR of 38.8 months

C., Kuehne, A., Zamboni, N