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In R161H mice, broad-spectrum antibiotic treatment reduced intestinal Th17 cell activation and alleviated uveitis, while in vitro studies demonstrated that bacteria-rich intestinal extracts directly activated IRBP-specific T cells, highlighting the role of gut microbial antigens in driving autoreactive T cells (102)

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Accordingly, SARSCoV2 genome and its products reprogram and dysregulate human metabolism at transcription, translation, and post-translational modification (PTM) levels 17,18,19,20

10.3390/vaccines9040395 Vaccines 260 ZhangX.MengD.LiH.LiX.LiJ.HuP.et al

Mader, J

Opt Mater 97:109356