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In vivo studies, two trials performed by (Lenzi et al

10.3390/ijms20112723 76 ManciasJ

3.1.1.2 Curcumin and the Wnt/ -catenin signaling pathway The Wnt/ -catenin pathway governs cellular proliferation, adhesion, and differentiation

Glutathione plays a role in helping to restore vitamin C to its active form, allowing it to continue working rather than being used up after a single reaction

Specifically, EGCG inhibits the phosphorylation of the 705th tyrosine residue of STAT, and protein kinase C delta (PKC-delta), effectively blocking STAT1 activity