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doi: 10.3389/fmicb.2023.1166518 6

To conclude, iron metabolism and lipid peroxidation contribute to the occurrence of ferroptosis, and eventually up-regulate inflammation

With ongoing advancements in nanotechnology, these innovative drug delivery systems hold immense potential to revolutionize the treatment of ophthalmology diseases, offering improved therapeutic outcomes and enhancing the quality of life for patients

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Conversely, SIRT2 activation may decrease acetylation of PEPCK 1, enhancing its stability, while deacetylating FOXO1 and PGC-1 to upregulate transcription of glucose metabolism-related bio-enzymes, resulting in the inhibition of gluconeogenesis (43)