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FIGURE 4 4.3.2 Cell membrane-coated NPs In particle surface modification, a top-down biomimetic strategy was investigated by coating biodegradable polymer NPs with natural cell membranes (CMs) to enable long-acting drug delivery and targeted accumulation at lesions (as shown in Figure 5)

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Given its associations with AD status, cognitive decline risk and brain volume, we asked whether the CognitionBrain aging model could be used in combination with other biomarkers of AD and predictors of cognitive decline, including plasma pTau-181 (ref