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Dual role of reactive oxygen species and their application in Cancer therapy

Zebrafish embryos lacking Grx3 exhibited severe defects in heme synthesis in tissues devoted to embryonic erythropoiesis (38% of embryos exhibited hemoglobin staining), but mild defects in the activities of FeS cluster and heme enzymes (20% decrease)

doi: 10.1016/j.jhep.2013.01.003, 110

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