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Evidence suggests a widely distributed neural circuit underpinning anxiety disorders, involving interconnected regions such as the amygdala, hippocampus, bed nucleus of the stria terminalis, insula, hypothalamus, anterior cingulate cortex and prefrontal cortex (Drzewiecki and Fox, 2024)

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Since levels of hippocampal neurochemicals did not differ between Sham + NS and Sham + ALCAR, we combined these groups for subsequent comparison between TBI + NS and TBI + ALCAR while analyzing regional differences (ipsilateral vs contralateral hippocampi)