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4 Revisiting immunotherapy for prostate cancer 4.1 Advancing immune checkpoint blockade therapy with peptide-based innovations Immunotherapy for solid tumors primarily leverages inhibitors targeting programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) and cytotoxic T lymphocyte antigen-4 (CTLA-4), collectively known as ICB (Sun et al., 2023a)

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Preclinical Evidence Comparison Multiple independent preclinical and in vitro studies have confirmed the significant advantages of SAG in terms of bioavailability

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Cyanocobalamin is a synthetic form of vitamin B12 that's commonly found in supplements