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Disclosures: Basundhara Das: Nothing to Disclose, Sachin Sharma: Nothing to Disclose, Maryam Shaikh: Nothing to Disclose, Bornika Roy: Nothing to Disclose, Sampa Ghose: Nothing to Disclose, Subhrajit Biswas: Nothing to Disclose 2042 MFAP2 ABLATION RETARDS HEPATIC FIBROSIS REGRESSION BY ORCHESTRATING EXTRACELLULAR MATRIX AND INFLAMMATION Wen Zhang 1 Wenyue Wu 1 Ning Zhang 1 Hong Li 1 Yameng Sun 1 Xiaodong Ge 2 Hui Han 2 Shuyan Chen 1 Anjian Xu 1 Sai Santosh Babu Komakula 2 Chao Wang 2 Nithyananthan Subramaniyam 2 Qi Han 1 Xuzhen Yan 1 Aiting Yang 1 Natalia Nieto 2 Hong You 1 Wei Chen 1 , 1 Beijing Friendship Hospital, Capital Medical University, 2 University of Illinois at Chicago Background: Microfibril- associated glycoprotein 1 (MAGP-1) is a glycoprotein involved in extracellular matrix (ECM) remodeling

PNAS 110(48):1932419329

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Dietary interventions that reduce ultra-processed food intake and prioritize minimally processed nutrient-dense foods may represent a feasible, low-risk strategy to support mental health by restoring lipid balance and reducing neuroinflammatory burden

Training approach Resistance training is crucial: Lift weights 3-5x per week