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found no CHAC1 upregulation after exposing HT-1080 (fibrosarcoma cell line) and Calu-1 (non-small-cell lung cancer) cells to artesunate, whereas in more recent studies, a significant increase in CHAC1 expression in Burkitts lymphoma cells was observed (Wang et al., 2019)

10.1073/pnas.96.26.14967 49 SuiX.ZhangR.LiuS.DuanT.ZhaiL.ZhangM.et al (2018)

(1977b) Untitled and unpublished report from Product Safety Labs, USA

Hepatic lobules of rats exposed to aspartame at 150 mg/kg bw for 30 days exhibited a confused parenchymal architecture, some hepatocytes had infrequent nuclei and a vacuolated cytoplasm, and blood sinusoids were dilated and congested

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