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High levels of GFAT predict a poor prognosis in patients with PDAC [74]

Free radicals are forms of oxygen missing an electron and are highly reactive with everything they come into contact with, including healthy cells and DNA

FAAHfatty acid amide hydrolase

The inner membrane contains a variety of ion channels and transporters as well as mitochondrial enzyme systems (Liu et al., 2018

Therefore, there is a possibility that high levels of Kbhb might disrupt the normal activity of the target proteins and that -hydroxybutyrylation is an inducible PTM that can affect protein function