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Vitamin C oder Vitamin E

If skin does look or feel worse after starting 1% GHK-Cu Face and Skin Serum, reducing frequency further (back to every other day, or every third day, for example) rather than stopping entirely is a reasonable next step if the change is mild, since it allows the skin to continue adjusting at a slower pace

First-pass metabolism: Anything that survives the gut must pass through the liver, where it may be further processed before reaching the rest of the body

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Wetter, DA et al