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388,389 Intracellular lipid accumulation can lead to mitochondrial dysfunction, which not only reduces the number of mitochondria but also exacerbates lipid accumulation, creating a vicious cycle

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[DOI] [PMC free article] [PubMed] [Google Scholar] Attal N, Marrero E, Thompson KJ, McKillop IH

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I always joke if those studies have been done over here, everyone would already know about it