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Is CYP2C70 the key to new mouse models to understand bile acids in humans

Paradoxically, they also upregulate ETC activity and SRC, likely driven by elevated Pgc-1 and suppressed mitophagy (Atg101, Ulk1) (Quinn et al, 2018, 2020)

Johansson P, berg D, Johansson J-O, Mattsson N, Hansson O, Ahrn B, Isgaard J, berg ND, Blennow K, Zetterberg H, Wallin A, Svensson J (2013) Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimers disease

Gastroenterology 125 , 380388 (2003)

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Conjugated linoleic acid reduces body fat in healthy exercising humans