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(ii) the inclusion of patients receiving antiparkinsonian therapy may have influenced the metabolomic profiles

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Tramiprosate did not show a significant effect in ApoE 3/3 organoids while it led to a downregulation of carnitines (CAR), lysophosphatidylcholines (LPC-O) and oxidized phosphatidylethanols (PE-O), as well as an upregulation of ceramide (CER) in ApoE 4/4 (Fig

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Research areas include: Tendon and Ligament Injuries: Studies in rodent models have examined BPC-157's effects on: Achilles tendon healing following surgical transection Ligament repair and functional recovery Tendon-to-bone healing in rotator cuff injury models Reduction in adhesion formation during tendon healing Extrapolation to canine cruciate ligament disease (particularly cranial cruciate ligament rupture, one of the most common orthopedic conditions in dogs) represents a theoretical application requiring specific veterinary research

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