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The absence of an IGF-1 effect on early postnatal brain growth is consistent with observations that brain growth was not negatively affected until P40 in IGF-1 knock-out mice (Cheng et al., 2000)

This work was supported by the Guangdong Basic and Applied Basic Research Foundation (No.2022A1515110790 and 2024A1515012478)

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Another promising approach is represented by the use of probiotics, i.e

It restores normal nerve function and supports red blood cell production by correcting Vitamin B12 deficiency

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