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Feature · Product Review
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Apart from fundamental competition for nutrients required by cancer cells and immune cells in TME, metabolic pathways change in tumor cells may influence tumor-infiltrating immune cells, and different immune cell subgroups in TME have specific metabolic characteristics (282)

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The declining levels of IGF-1 in GF mice are associated with retarded linear growth, reduced body weight, and impaired bone formationincluding shorter femur length, lower cortical bone density, and reduced trabecular bone densityall of which indicate that GM plays an important role in optimizing growth

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