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Ligature side of the saline-treated group ( Fig

Method The local tolerance upon subcutaneous administration of the co-formulations described in table 23a and 23b was studied in 8 live minipigs, by evaluation of the resulting skin lesions 6 days (necropsy) after subcutaneous administration of sample sizes of 750pl using syringes equipped with 25 G sized needles and 5mm stoppers

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4 Discussion Apixaban has multiple routes of elimination, including CYP-mediated metabolism, renal excretion, biliary excretion, and direct excretion into the intestine [11, 22]

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It plays an important role in supporting detoxification pathways and healthy cellular function