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Genes involved in signal transduction and immunological response, as well as the expression of certain miRNAs (miR-145, miR-148-5p, and miR-592), were shown to be altered in tandem with GPER activation, as was the extracellular-signal-regulated kinase (ERK) signaling pathway (251)

The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

Methods Relevant articles were reviewed in databases of PubMed and Web of Science

Blood 106:316a, 2005

In addition, some insects, such as Apis cerana , Spodoptera exigua and Bombus ignites , can also initiate the corresponding oxidative stress mechanism when, for example, they encounter heavy metals and toxic compounds [20,21,22]