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Four studies were controlled trials, 561,623,625,626 while 1 was a case-control study

By using a multi-IAC column (6-in-1), Rubert et al

One of the mechanisms by which senescent cells escape from the immune response is made through the overexpression of the histocompatibility antigen alpha chain E (HLA-E) that bind to NKG2A, an inhibitor receptor expressed on Natural Killer cells (NK) 54 and CD8 + T cells, leading to the inhibition of SnCs recognition

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Immune microenvironment in intervertebral disc degeneration: pathophysiology and therapeutic potential

doi: 10.1101/602649 150