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We examined this possibility using siRNAs against each CED component and four different types of misfolded polypeptides: polypeptidyl-puro (one of the DRiPs 37,38

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Each subsequent trial was separated by at least 3 days as a washout period and followed identical study procedures, except for the consumption of a different vitamin C or placebo formulation (see Fig

Ensuring batch-to-batch consistency in particle size, drug loading efficiency, surface chemistry, and release kinetics is critical for predictable therapeutic outcomes and regulatory approval