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Gd-Cy7-PTP/RGD was introduced as a pancreatic cancer-targeted probe by covalently conjugating Cy7 with an MR contrast agent, Gd (III)

Protoplasmic astrocytes may accumulate and remove -synuclein, thus exercising neuroprotection 211 , although overload with -synuclein may cause mitochondrial damage while aggregated -synuclein may spread through astrocytic syncytia 212,213