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Description

Bogan KL, Brenner C

Designed to support sterile preparation and handling in laboratory and controlled-use settings

Pre-experiments revealed cytotoxic effects of roxadustat on neurons at concentrations of 50 M (Figure S5A), whereas the viability of astrocytes remained unaffected by roxadustat applied at a dose of 5 to 100 M (Figure S5B)

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It was tested in a large myocardial infarction trial (CIRCUS trial) but did not significantly reduce infarct size in humans

Additional context is available in the peptides for anti-aging category and the fast injury healing category, both of which overlap with psoriasis-relevant research