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Description

GDF-15 is induced under stress conditions to maintain cell and tissue homeostasis

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This is a protein that is low expressed in normal tissues and significantly increased in fibrotic tissues and is an ideal target to mark and detect myofibroblast activation [282, 283]

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Methods Enzymol 233:357363

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Overdose deaths associated with polyintoxication are increasingly reported

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DKK-1 induces LRP5/6 endocytosis in cardiomyocytes, causing GPCR signalling disorder and promoting ischaemia-induced DNA damage in cardiomyocytes

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