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By combining L-DOPA with COMT and/or MAO-B inhibitors, a physician may be able to reduce the dose of L-DOPA required to relieve symptoms, and widen dose intervals, which is more convenient for the patient

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Structurally, iGluRs are transmembrane proteins composed of four subunits that form a central ionic pore comprised of an extracellular amino-terminal domain, an extracellular ligand-binding domain, four transmembrane domains, and an intracellular carboxyl-terminal domain (Traynelis et al., 2010)

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Peptides like BPC-157 and TB-500 are known to promote joint health by regenerating tissue and reducing inflammatory cytokines

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