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With studies characterising reduced infarct size, improved cardiac function, promotion of cardiac progenitor cell migration, cardiomyocyte survival through PI3K/Akt anti-apoptotic signalling, and stimulation of new vessel formation in infarcted myocardium

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pmid:28044066

Lu and P.A

Inhibition of either the Notch or Wnt pathway at early cochlear development results in diminished prosensory regions and prevented hair cell differentiation, suggesting that the pathways may intersect at least at this developmental stage (Brooker et al., Lgr5 -positive cells in the neonatal cochlea in vitro (Bramhall et al., Lgr5 -positive cells, as the auditory and vestibular organs age