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doi: 10.3389/fneur.2025.1643305 Received 08 June 2025 Accepted 20 August 2025 Published 22 September 2025 Volume 16 - 2025 Edited by Marcelo Mendona, Champalimaud Foundation, Portugal Reviewed by Ins Figueira, NOVA University of Lisbon, Portugal Alina Sacarescu, Grigore T

The increase in plasma cystine in the previous pilot study with normal-weight individuals was suggested to be due to compensatory mechanisms, including decline in the urinary excretion of tCys, and potential activation of CDO , which is the rate-limiting enzyme in oxidation of cysteine to taurine [33]

The introduction of serum therapy for diphtheria was a major breakthrough because at that time the disease was a significant killer with approximately 50,000 children dying from it in Germany each year

doi: 10.3390/nu14122481