Variation in redox state, as represented by the intracellular GSH:GSSG ratio, can have profound clinical implications, enhancing cell signalling and even cell death
If this finely tuned balance in BH4 concentration is perturbed, several biological systems are compromised, resulting in impaired neurotransmission, immune responses, metabolism, and vascular activity (Figure 5)
IF quantification was performed using Volocity Software to determine either Mean Fluorescent Intensity or PCC
Science 125:884885 Mller J (2003) Effects of growth hormone on fluid homeostasis
The effects of coenzyme Q10 supplementation on performance during repeated bouts of supramaximal exercise in sedentary men
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