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doi: 10.1146/annurev-pathmechdis-012418-013058 96 SteubeKGMeyerCDrexlerHG

Additionally, the role of non-classical ferroptosis regulators (e.g., FSP1, DHODH) in CIN is entirely unexploredwhether these pathways compensate for GPX4 dysfunction in CIN or if their dysregulation exacerbates susceptibility remains unknown, limiting the development of multi-targeted interventions