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An animal study on gut microbial composition revealed significant -diversity differences between chronic unpredictable mild stress (CUMS) rats and control rats (Meng et al., 2025), which aligns with observational findings (McGuinness et al., 2022)

Application of multi-omics techniques to investigate the anti-cancer properties of silibinin Recent advancements in omics technologies, including genomics, transcriptomics, proteomics, and metabolomics, have significantly enhanced the capability to elucidate the anti-cancer mechanisms of silibinin [957, 958]

This could also impair your glutathione levels and detoxification

"Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms?"

A review published in the Journal of Environmental and Public Health, in Oct 2011 also found that eating more alkaline foods such as fruits and vegetables has health benefits