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Unlike most mammals, humans cannot synthesize vitamin C endogenously due to the absence of the enzyme L-gulono--lactone oxidase, necessitating dietary intake from sources like citrus fruits, leafy greens, and supplements

Some PFIC gene variants in ABCB11, ABCB4, and TJP2 have been reported in patients with liver tumors

First, about 90% of the drug is processed by the body through a process called glucuronidation, which does not produce dangerous byproducts

[DOI] [PubMed] [Google Scholar] 97.Zhong L., Arnr E.S., Holmgren A

Its important to seek detox in a clinical and professional environment as withdrawal symptoms have to be managed and monitored

Yeh T-H, Tu K-C, Wang H-Y, Chen J-Y