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1 Irrespective of the specific urate-lowering therapy (ULT) selected, fundamental principles entail commencing treatment concurrently with prophylaxis and initiating with a conservative dosage, followed by systematic monitoring of serum uric acid levels and subsequent dose adjustment until the therapeutic target is attained

As a worst-case estimate assuming a 100-g tablet containing 137 g of aluminum, an individual weighing 70 kg would need to consume at least 511 tablets daily to reach the MRL for aluminum

The worst-case pattern is a patient harmed by an unapproved peptide and an insurer who declines coverage because the treatment fell outside the standard of care or federal compliance

Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study

Low-carbohydrate diets, primarily composed of animal-based protein and fat, such as lamb, beef, pork, and chicken, have been linked to higher mortality rates