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(2) excessive production of matrix metalloproteinases (MMPs), which collectively exacerbate inflammation and contribute to cartilage degradation [11]

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Combination therapy group received PEG-IFN-2b for 12 weeks followed by TDF add-on for 36 weeks, TDF monotherapy group received TDF for 48 weeks and control group were followed-up without any antiviral treatment (Figure 1A)

10.1080/14786419.2017.1385015 18 BahmanA

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Autophagy in hypoxia-ischemia induced brain injury