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PMID: 1405716

Review Your Treatment Plan With a Clinician Discuss dosing, side effects, safety concerns, and your treatment goals before starting tirzepatide or changing your weekly dose

In nervous tissue, where glutamate is present in concentrations higher than in the other tissues, GLUD1 appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification

Furthermore, increased ROS may lead to inflammation, hypertrophy, cell proliferation, apoptosis, migration, and fibrosis [53], while also producing endothelial dysfunction [46]

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