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Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine

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MacAulay GC, Galland BC, Boucher SE et al (2020) Impact of type 1 diabetes mellitus, glucose levels, and glycemic control on sleep in children and adolescents: a case-control study

These insights emphasize the complex and varied potential ways in which DSIP might impact sleep and stress, though further investigation is essential to fully delineate its biological functions and research potential

GHK-Cu helps repair and reset the DNA, leading to improved tissue growth [2]