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(2014) studied 60 patients with phobic-anxiety and somatoform disorders

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This paradox may be explained by the increased insulin resistance and the compensatory intra-portal hyperinsulinemia causing increased hepatic GH sensitivity that increases serum IGF-I and blunts pituitary GH secretion via the negative feedback loop

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248,251,252 This mechanism is particularly evident in the use of GLP-1-based drugs, such as GLP-1RAs, in the treatment of T2DM

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CSE was independently associated with ESR (OR = 2.16

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