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For example, the -secretase inhibitor MK0752, which targets Notch signaling, has demonstrated gastrointestinal toxicity, including diarrhea and nausea, in multiple clinical trials for solid tumors and central nervous system malignancies

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Heterogeneity of T cells in periapical lesions and in vitro validation of the proangiogenic effect of GZMA on HUVECs

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Neuropharmacology 112 , 307323 (2017)