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While there may not be a direct cause-and-effect relationship, an unexplained or persistent Vitamin B12 deficiency warrants further exploration to rule out a serious condition, even a hidden malignancy

277 Direct inhibitors of the IKK/NF-B pathway may confer clinical benefits for degenerative changes associated with both progeroid syndrome and normal aging

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Ma Z, Ma Y, Cao X et al (2023) Avenanthramide-C activates Nrf2/ARE pathway and inhibiting ferroptosis pathway to improve cognitive dysfunction in aging rats